Hjernen og ryggmargen mangler et signal og skrur opp sin sensitivitet. Da vil gentleman kunne plukke opp mye annet støy som kan oppfattes som smerter. Etter hvert vil kroppen kunne tilpasse seg situasjonen og skru ned sensitiviteten igjen, forklarer Tjølsen.Han legger til at i sjeldne tilfeller kan gentleman få komplekst regional smertesyndrom.
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